In my testing, someone claimed that there wasn't enough contrast between some of the form elements and the background color. The user complained about "white on white", even though it is white on light gray.
Anyway, so I started investigating what it would take to change the background color. Answer: not much, just a simple change of the css. However, with this change the nice taskbar in the upper right doesn't look so nice because it doesn't fade from white to the background color.
So I created a png image (attached) that uses transparency instead of the gif that is currently there. Replacing the gif with the png has no downsides that I can see. It does add these benefits:
support png transparency.
To use the png you will need to drop the png in the skins/default/images/ directory and change the #taskbar definition in skins/default/common.css (around line 121) to use taskbar.png instead of the .gif version.
Thanks, Jacob Brunson Department of Chemistry, BYU